There has been news this week of what seemed at first sight like a major setback for Alzheimer’s researchers and patients seeking a disease-modifying drug.
The FDA here in America had its own debacle years ago regarding an accelerated approval of an Alzheimer’s drug Aduhelm. And, as you point out, what a drug company regards as a favorable therapeutic response, may not be meaningful or even noticeable by patients or caretakers. Finally, this amyloid issue is not new. Is amyloid actually a cause or merely an effect? If the latter, as many suspect, then targeting it with drugs may be misfiring.
Thanks for sharing Rory. I'm close to a family member having a diagnose. We are at the stage where we can get the blood test for Alzheimers but have been told it might give a false positive or negative so not sure how to proceed after that. It is always challenging when new drugs come on the market offering hope but side effects too.
The FDA here in America had its own debacle years ago regarding an accelerated approval of an Alzheimer’s drug Aduhelm. And, as you point out, what a drug company regards as a favorable therapeutic response, may not be meaningful or even noticeable by patients or caretakers. Finally, this amyloid issue is not new. Is amyloid actually a cause or merely an effect? If the latter, as many suspect, then targeting it with drugs may be misfiring.
Thanks for sharing Rory. I'm close to a family member having a diagnose. We are at the stage where we can get the blood test for Alzheimers but have been told it might give a false positive or negative so not sure how to proceed after that. It is always challenging when new drugs come on the market offering hope but side effects too.
website does not work. 'sign here' not working
Aaagh. Will fix when I get to a computer
It’s working fine for me